Fstl1 macrophage
WebAug 5, 2024 · An MSC-macrophage co-culture system was constructed to further confirm the role of FSTL1 in the immunosuppressive capacity of MSCs. RNA sequencing was used to screen target genes of FSTL1. FSTL1low MSCs had comparable gene expression for surface markers to wildtype but limited differentiation and migration capacity. WebDec 1, 2024 · FSTL1 is reported to induce the release of macrophages- and fibroblasts-derived inflammatory cytokines [14], demonstrating that FSTL1 plays a pro-inflammatory role. Zhang et al. found that miR-32-5p facilitates the survival of M.tb pathogen and restrains the release of inflammatory factors in macrophages, and FSTL1 overexpression …
Fstl1 macrophage
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WebOf particular note was that several gene regulation and macrophage antiinflammatory genes were differentially expressed in an FSTL-1–dependent manner, including the nuclear orphan receptor Nr4a1, also known as Nur77. ... It would have been worth examining FSTL1 SNPs in other cohorts and populations, as well as measuring FSTL-1 levels ... WebMay 1, 2014 · Myeloid-specific FSTL1-knockout (FSTL1 M-KO ) mice were constructed to explore the function and mechanism of macrophage FSTL1 in 3 murine models of liver fibrosis induced by carbon tetrachloride ...
WebFeb 9, 2024 · First, macrophage FSTL1 expression was assessed in patients and mice with liver fibrosis/cirrhosis. Second, we created a myeloid-specific FSTL1-knockout (FSTL1 M … WebCD51 + CD61 (Integrin alpha V + Integrin beta 3) CD51 / Integrin alpha V. CD52
WebFeb 9, 2024 · Objective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented. WebHuman FSTL1 ELISA Kit is a Sandwich (quantitative) ELISA for the measurement of Human FSTL1 in Human Cell culture supernatant, Serum, Cell ... It was suggested that fibroblast-secreted FSTL1 acts on macrophages to increase TNF and IL1B production and IL6 activity. Platform. Pre-coated microplate (12 x 8 well strips) Properties. Storage ...
WebFollistatin-like 1 (FSTL1) functions as a pivotal modulator of inflammation and is implicated in many inflammatory diseases such as rheumatoid arthritis. Here, we report that FSTL1 is strongly upregulated and secreted during osteoclast differentiation of bone marrow-derived macrophages (BMMs) and th …
WebAug 5, 2024 · An MSC-macrophage co-culture system was constructed to further confirm the role of FSTL1 in the immunosuppressive capacity of MSCs. RNA sequencing was … bug bites after applying sunscreenWebJan 28, 2014 · FSTL-1 promotes caspase-1 activation in monocytes and macrophages. Human U937 cells stably transfected with plasmid encoding FSTL1 or a control plasmid were treated with LPS (200 ng/mL) or differentiated into U937 macrophages with PMA (0.5 mM). FSTL1-transfected mouse macrophage RAW264.7 cells were stimulated with or … bug bites affect blood sugarWebDec 10, 2024 · FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM2. Follistatin-like 1 (FSTL1) interacts with Wnt ligands and Frizzled receptors to enhance Wnt/beta-catenin signaling in obstructed kidneys in vivo. Knockdown of FSTL1 inhibits microglia activation and alleviates … bug bites after cleaningWebObjective: Asthma, a well-known disease with high morbidity, is characterized by chronic airway inflammation. However, the allergic inflammation mechanisms of follistatin-like … croscill curtain hardwareWebObjective Follistatin-like protein 1 (FSTL1) is widely recognised as a secreted glycoprotein, but its role in modulating macrophage-related inflammation during liver fibrosis has not been documented. Herein, we … bugbites after moving into rental homeWebMar 15, 2024 · FSTL1 silencing largely overturned miR-579-3p knockdown-induced effects in M.tb-infected THP-1 macrophages. Circ_0001490 acted as miR-579-3p sponge to up-regulate FSTL1 in THP-1 macrophages. In conclusion, our results demonstrated that circ_0001490 suppressed M.tb survival and promoted the viability and inflammatory … croscill curtains redWeb卵泡抑素样蛋白1（follistatin-like protein 1,FSTL1）是一种分泌型细胞外基质糖蛋白,在心血管疾病、自身免疫性疾病、肿瘤、炎症等疾病模型的发生、发展和转归过程中发挥重要作用,参与多种生物学过程,包括细胞增殖、凋亡、组织分化等。FSTL1在脊椎动物神经系统中调节神经胚形成和神经元分化诱导;参 croscill dry cleaning