Chaarted high volume definition
WebJan 11, 2024 · High-volume disease per CHAARTED criteria was defined as the presence of visceral metastasis or ≥4 bone lesions with ≥1 beyond the vertebral bodies and pelvis; … WebFeb 3, 2024 · Recent landmark randomized trials (CHAARTED and LATITUDE studies) have highlighted potent upfront therapy for “high-volume” and “high-risk” metastatic castration-naïve prostate cancer (mCNPC). However, treatment response shows racial differences. We aimed to propose a novel definition for “high-volume” prostate cancer …
Chaarted high volume definition
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WebFor example, the CHAARTED trial defined high volume disease as the presence of visceral metastases and/or ≥4 bone lesions with ≥1 lesion beyond the vertebral bodies and pelvis. This study revealed the survival benefit of the upfront use of docetaxel only existed in mPC patients with high volume disease but not in those with low volume ... WebOct 21, 2024 · The planning target volume consisted of the prostate only, with an 8 mm margin posteriorly and a 10 mm margin elsewhere. ... if median survival were roughly 6 years. If about 60% of patients had a high metastatic burden, we anticipated the subgroup analysis would have roughly 88% power for failure-free survival (HR 0·80) if median …
WebMay 21, 2024 · Metachronous: patients recorded as M0 at first diagnosis of prostate diagnosis and later developed mHSPC on CT A/P or bone scan; de novo: first presentation of prostate cancer was with metastatic disease; high versus low volume of mHSPC as per the CHAARTED definition. WebFeb 13, 2015 · Intriguingly, patients with high-volume disease (n = 520), defined as 4 or more bone metastases, liver or lung metastases, who received ADT plus docetaxel concurrently had even better relative ...
WebFeb 1, 2024 · Just as a quick reminder, the CHAARTED trial divided patients newly diagnosed with metastatic prostate cancer into two subsets: those with “high … WebThe first analysis of the STAMPEDE M1 RT comparison 1 identified that prostate RT was more effective in the prespecified low-burden subgroup based on the CHAARTED definition. 10 However, it was not clear how this treatment effect varied based on bone metastasis counts and whether a higher threshold could be selected. In this study, we …
WebDec 1, 2024 · Defined as the presence of two of the three following factors: GS ≥8, ≥3 bone lesions, measurable visceral metastasis. The number (percentage) of patients who …
WebFollowing chart review for basic demographics and clinical features, the authors retrospectively applied the eligibility criteria of CHAARTED (both high-volume [HV] and … electric power floor scrubberWebApr 1, 2024 · Since 2014, 95 patients with newly diagnosed mHNPC were prospectively registered. For this study, they were categorized as having high-volume (HVD) vs. low-volume (LVD) and high-risk (HRD) vs. low-risk disease (LRD) according to the definition of CHAARTED and LATITUDE, respectively. Agreement was tested using Cohen’s κ … food truck pos system costWebHigh definition (HD) voice, also known as wideband voice, is an audio technology that transmits audio over a wider range of frequencies with a higher sampling rate to provide … electric power flywheelWebFeb 26, 2024 · After extraction of baseline patient characteristics, we applied the eligibility criteria of CHAARTED (both high-volume [HV] and low-volume [LV] definition), … electric power floor scraperWebApr 4, 2024 · National Center for Biotechnology Information electric power finlandWebMay 20, 2024 · The median (range) age was 71.5 (50–80) years old, and 11/12 (91.7%) were defined as the CHAARTED high-volume group. Eleven (91.7%) had 3 or more bone metastases, and 4 (33.3%) had visceral metastasis. The initial dose of docetaxel was 70 or 75 mg/m 2 and was scheduled to be administered for up to 6 courses every 3 or 4 weeks. electric power floor craneWebThe definition of high-volume disease used for this protocol was a combination of features from prior classifications. All the definitions included the presence of nonnodal, soft-tissue visceral ... electric power fittings